| 刊名 | Medicinal Plant |
| 作者 | Xiaoqiang ZHANG1,2*, Wenjing LU3,4, Peifang LI1,5 |
| 作者单位 | 1. The First School of Clinical Medicine, Shanxi University of Chinese Medicine; 2. Department of Rheumatology, Shanxi University of Chinese Medicine Affiliated Hospital 3. Laboratory of Gene Expression Regulation in Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine; 4. Shanxi Cross-Innovation Engineering Research Center for Traditional Chinese Medicine; 5. Department of Spleen-Stomach Diseases, Shanxi University of Chinese Medicine Affiliated Hospital |
| DOI | DOI:10.19600/j.cnki.issn2152-3924.2026.010.007 |
| 年份 | 2026 |
| 刊期 | 1 |
| 页码 | 34-39 |
| 关键词 | Stomach, Knee, Helicobacter pylori (Hp), Knee osteoarthritis (KOA), Combined bi of body constituents and zang organs, Stomach and knee joint treatment |
| 摘要 | The existence of the “stomach-knee axis” and the potential independent association between “Helicobacter pylori (Hp) infection and knee osteoarthritis (KOA)” have been substantiated through multiple lines of evidence, including epidemiological studies of the “stomach-knee axis”, investigations into the pathological mechanisms linking “Hp infection and arthritis”, as well as research on co-treatment drugs and the anti-inflammatory mechanisms relevant to “gastritis-arthritis”. The investigation into “stomach and knee joint treatment” is grounded in the concept that the “stomach-knee axis” aligns with the “combined bi of body constituents and zang organs” theory. Clinical cases have demonstrated that therapeutic strategies of “stomach and knee joint treatment” can mitigate KOA damage by modulating the “stomach-knee axis” and eradicating Hp infection in the stomach. This study aims to contribute novel insights into the cross-system treatment of KOA. Further investigation into the “stomach-knee axis” may yield innovative strategies for the prevention and management of KOA, potentially through the eradication of Hp. |
