Screening for Antioxidant Phenolic Compounds from Polygonum capitatum
刊名 Medicinal Plant
作者 Yan LIN
作者单位 State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University; University Engineering Research Center for the Prevention and
DOI 10.19601/j.cnki.issn2152-3924.2024.04.001
年份 2024
刊期 4
页码 1-3,10
关键词 Polygonum capitatum, Phenolic compounds, Antioxidant activity
摘要 [Objectives] To discover antioxidant natural products from the famous Hmong medicinal plant Polygonum capitatum. [Methods] The antioxidant activities of the isolated components were evaluated by ABTS and DPPH assays. [Results] A total of 27 free phenolics were isolated form P. capitatum. Then the in vitro antioxidant potential of these components was evaluated according to the DPPH and ABTS radical scavenging assays. Among them, five compounds (13, 14, 17, 23, and 25) showed most significant ABTS radical-scavenging activity (IC50 values of 3.81-15.09 μg/mL). And 12 components (1, 2, 6, 7, 9, 12, 13, 14, 16, 17, 23, and 25) showed notable radical scavenging activity against DPPH (inhibition rates >88%). [Conclusions] Most of the above bioactive compounds were reported for the first time.