| 刊名 | Medicinal Plant |
| 作者 | Yumei ZHANG， Yulin ZHAO， Yanmei QIN， Jialing WEI， Xiang QIN， Suoyi HUANG |
| 作者单位 | College of Clinical Medicine, Youjiang Medical University for Nationalities； Key Laboratory of Research on Characteristic Ethnic Medicine in the Youjiang River Basin of Guangxi Colleges and Universities； College of Pharmacy, Youjiang Medical University for Nationalities |
| DOI | 10.19601/j.cnki.issn2152-3924.2024.01.011 |
| 年份 | 2024 |
| 刊期 | 1 |
| 页码 | 45-47 |
| 关键词 | Radix Puerariae, Radix Rehmanniae, Compatibility, Hypoglycemic effect, Blood lipids |
| 摘要 | [Objectives] To explore the effects of the compatibility of Radix Puerariae and Radix Rehmanniae on blood glucose and blood lipids in diabetic mouses. [Methods] Diabetic mouse model was established. The body weight and fasting blood glucose of mice were measured after 7 and 14 d of administration, and the biochemical indicators of blood lipids (TC, HDL-C, and LDL-C) were detected after 14 d of administration. [Results] Compared with the Radix Puerariae group and Radix Rehmanniae group, the compatibility group (1：2) had the best hypoglycemic effect (P<0.05), and TC and LDL-C in the compatibility group (2：1) significantly decreased (P<0.05), while HDL-C in the compatibility group (1：1) significantly increased (P<0.05). [Conclusions] Radix Puerariae, Radix Rehmanniae and their combination can reduce the blood glucose of diabetic mice. The compatibility group (1：2) had a significant hypoglycemic effect (P<0.05), and LDL-C in the compatibility group (2：1) significantly declined, while HDL-C in the compatibility group (1：1) rose significantly. |
