| 刊名 | Medicinal Plant |
| 作者 | Di LIANG, Weiwei CHEN, Yuzhou PANG, Jiangcun WEI |
| 作者单位 | 1.Guangxi International Zhuang Medicine Hospital, Nanning 530201, China; 2.Guangxi University of Chinese Medicine, Nanning 530220, China |
| DOI | DOI:10.19600/j.cnki.issn2152-3924.2026.02.007 |
| 年份 | 2026 |
| 刊期 | 2 |
| 页码 | 29-32，40 |
| 关键词 | Zhuang Medicine Yishanhong Granules, Orthogonal test, Formulation process |
| 摘要 | [Objectives] To screen the optimal formulation process for Zhuang medicine Yishanhong Granules. [Methods] An L9(34) orthogonal design was employed to optimize the granulation process, with comprehensive assessment based on the granule yield, moisture absorption, flowability, and color uniformity. The factors investigated included the amount and ratio of excipients, and the mesh size of the sieve. [Results] The optimized parameters were as follows: a 3:2 ratio of dextrin to mannitol as excipients, a 1:3 ratio of extract to excipients, and a 14-mesh sieve. Under these conditions, Zhuang Medicine Yishanhong Granules were successfully obtained. [Conclusions] The optimal formulation process for Zhuang medicine Yishanhong Granules was determined. The granules prepared under these conditions exhibited a satisfactory formation rate, along with favorable properties in terms of moisture absorption, flowability, dispersibility, and color uniformity. This process is rational and feasible, thereby providing a reliable basis for industrial production. |
