| 刊名 | Medicinal Plant |
| 作者 | Miao YANG， Chaohao GU， Qiling LI， Zhiqiang HUANG， Hao LIU， Yanxi LAI， Zongyou CHEN， Kaimei ZHU |
| 作者单位 | Guilin Medical University； Guangxi Institute of Botany, Chinese Academy of Sciences |
| DOI | 10.19601/j.cnki.issn2152-3924.2023.05.008 |
| 年份 | 2023 |
| 刊期 | 5 |
| 页码 | 36-41 |
| 关键词 | Sophora japonica cv. Jinhuai, Quercetin, Penicillium, Fermentation process, Response surface methodology (RSM) |
| 摘要 | ［Objectives］To optimize the solid-state fermentation process of Flos Sophorae Immaturus by Penicillium with Sophora japonica cv. jinhuai as raw material. [Methods] The fermentation conditions were optimized by single factor experiment and response surface methodology with quercetin content as the dependent variable. [Results] According to the established model, the optimal fermentation process of Flos Sophorae Immaturus was obtained as follows: temperature 29.97 ℃, time 6.88 d, rotation speed 180.86 rpm, inoculation amount 3.93 mL, and the expected content of quercetin was 34.805 3 mg/g. Based on this, the fermentation parameters were adjusted, and the actual content was 33.67 mg/g, which was close to the predicted value. [Conclusions] The optimization of fermentation process of Flos Sophorae Immaturus by response surface methodology provides a reference for the development and utilization of this medicinal material. |
