| 摘要 |
[Objectives] To investigate optimal storage methods and shelf life determination for several representative bagged traditional Chinese medicine (TCM) decoctions under centralized preparation conditions in intelligent TCM pharmacies. [Methods] First, the nourishing formula was prepared and packaged in bags. Under the three storage conditions of 37 ℃ before cold storage (including full high temperature), cold storage before 37 ℃ (including full cold storage), and alternating 37 ℃ and cold storage, the 30 d cycle was investigated to determine the total microbial colony count, so as to determine a reasonable storage method of traditional Chinese medicine decoction. Secondly, five representative prescriptions were prepared and packaged in bags, stored under 37 ℃, room temperature and cold conditions. The investigation period was 30 d. The pH, total bacterial count and soluble solid content were measured, and the changes of each index were analyzed to obtain the shelf life of the bagged Chinese medicine decoction. [Results] First, the nourishing formula was investigated for 30 d. The microbial results of refrigeration after 1-2 d of 37 ℃, complete refrigeration and 37 ℃ cooling with an alternate interval of 2 d or less met the requirements, while the microbial results of refrigeration after 3 d or above of 37 ℃, refrigeration after 1-5 d and then 37 ℃, complete 37 ℃, 37 ℃ and cooling with an alternate interval of 3 d or above excessive microorganism. Second, under the condition of 37 ℃ storage, the pH of the five prescriptions decreased significantly, the total microbial colonies exceeded the standard, and the solid content decreased significantly. However, under the condition of room temperature and cold storage, the pH, total microbial colonies, and solid content of the five prescriptions remained stable. [Conclusions] The first is to refrigerate the decoction after 1-2 d of 37 ℃, completely refrigerate it, and refrigerate the decoction with an alternate interval of 2 d or less at 37 ℃. The shelf life can last for 30 d. Several storage conditions are conducive to guiding the development of the storage mode of the decoction. Second, under the conditions of cold storage, all the indexes were stable, and the shelf life of the five representative formulas was 30 d. |
