| 刊名 | Medicinal Plant |
| 作者 | Hao LIU， Yanxi LAI， Shengjiu GU， Kaimei ZHU |
| 作者单位 | College of Pharmacy, Guilin Medical University |
| DOI | 10.19601/j.cnki.issn2152-3924.2025.01.005 |
| 年份 | 2025 |
| 刊期 | 1 |
| 页码 | 23-26 |
| 关键词 | Third-generation cephalosporins, Process optimization, Nanotechnology, Green chemistry, Drug stability |
| 摘要 | The latest progress in the process optimization and stability improvement of third-generation cephalosporins in recent years was reviewed. The introduction of green chemistry, enzyme catalysis, nanotechnology, lyophilization, and nitrogen-filled packaging technologies can only improve production efficiency and reduce the generation of by-products, but also significantly extend the shelf life of drugs. In the future, process automation and intelligent technology will further optimize the large-scale production process, and the combination of nanotechnology and precision drug delivery will promote the improvement of effect in clinical applications. |
