| 刊名 | Medicinal Plant |
| 作者 | Yifan TIAN，Yuanlin KONG，Limin LI，Zhengming YANG，Chaoqin REN，Yongcang ZHANG，Yuan LIU，Yanfei HUANG |
| 作者单位 | College of Pharmacy, Qinghai-Tibetan Plateau Ethnic Medicinal Resources Protection and Utilization Key Laboratory of National Ethnic Affairs Commission of the People’s Republic of China, Southwest Minzu University； Sichuan Academy of Chinese Medicine Sciences； College of Resources and Environment； Medical College, Tibet University |
| DOI | 10.19601/j.cnki.issn2152-3924.2025.01.001 |
| 年份 | 2025 |
| 刊期 | 1 |
| 页码 | 1-10 |
| 关键词 | Meconopsis integrifolia (Maxim.) Franch, UPLC-Q-Exactive Orbitrap MS, Total flavonoids, Alkaloids, Phenolic acids |
| 摘要 | [Objectives] To analyze the chemical components of Meconopsis integrifolia (Maxim.) Franch total flavonoids (MITF). [Methods] The chemical components of MITF were identified by UPLC-Q-Exactive Orbitrap MS. The column was performed using ACQUITY UPLC HSS T3 (100 mm×2.1 mm, 1.8 μm) with 0.1% formic acid water (A)-acetonitrile (B) with gradient elution at 30 ℃, injection volume of 2 μL, and flow rate of 0.3 mL/min. Electrospray ion source adopted positive and negative ion detection mode with scanning range m/z 100-1 000. [Results] A total of 93 compounds were identified from MITF, including 57 flavonoids, 25 phenolic acids, 9 alkaloids and 2 others. Among them, dimethoxytaxifolin was identified as a possible new compound by SciFinder search, and 67 compounds were first identified in M. integrifolia. [Conclusions] This study provides a scientific foundation for clarifying the material basis of the efficacy of M. integrifolia and improving the quality standards. |
