| 刊名 | Medicinal Plant |
| 作者 | Jiuxu ZHAO，Wei XU，Huijun DU，Yu CHEN |
| 作者单位 | Department of Rehabilitation Medicine, Taihe Hospital, Hubei University of Medicine |
| DOI | 10.19601/j.cnki.issn2152-3924.2023.04.022 |
| 年份 | 2023 |
| 刊期 | 4 |
| 页码 | 86-89 |
| 关键词 | High-grade glioma, Intraoperative MRI, Meta-analysis |
| 摘要 | [Objectives] The paper was to comprehensively assess the available evidence on the diagnostic value of high-field intraoperative MRI (iMRI) for residual tumor in high-grade glioma (HGG) and its prognostic impact on HGG. [Methods] We conducted a systematic literature search of electronic databases including PubMed, Embase and Cochrane Library to identify eligible studies. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). The primary outcome was the gross total resection rate, with secondary outcomes including overall survival and 6-month progression-free survival. [Results] From a review of 132 candidate articles, we identified six articles with a total of 573 patients. The pooled risk ratio (RR) was 1.583 (95% CI: 1.235-2.029), indicating that high-field intraoperative MRI guided resection was associated with a reduced risk of 6-month progression-free survival, with a HR of 0.53 (95% CI: 0.348-0.806). The pooled HR of overall survival was 0.796 (95% CI: 0.581-1.089) between the two groups. [Conclusions] High-field iMRI appears to enable achievement of an ideal resection, although no strong evidence indicates that its application is associated with patient survival. Our study innovatively considered the effect of magnetic field intensity on tumor resection, and we found that 3 Tesla did not show a more favorable impact on improving the tumor resection rate compared with 1.5 Tesla. |
