| 刊名 | Plant Diseases and Pests |
| 作者 | Xichun HUANG, Quan QUAN, Junhao LI, Zhao NING, Hongye LI, Wenhui ZHAO, Chenghao JIN |
| 作者单位 | College of Life Science and Biotechnology, Heilongjiang Bayi Agricultural University |
| DOI | 10.19579/j.cnki.plant-d.p.2026.03-04.008 |
| 年份 | 2026 |
| 刊期 | 2 |
| 页码 | 34-37 |
| 关键词 | Astragalin, Anti-inflammatory, Anti-tumor, Antioxidant, Neuroprotective, Heart failure |
| 摘要 | Astragalin exhibits a range of biological activities. This review summarizes recent research on the effects of astragalin in anti-inflammatory, anti-tumor, antioxidant, neuroprotective, and cardiovascular protective contexts. Regarding its anti-inflammatory properties, astragalin primarily mitigates inflammatory responses by inhibiting the MAPK and NF-κB signaling pathways. In terms of anti-tumor activity, it modulates pathways such as PI3K/AKT and NF-κB to suppress the proliferation and migration of various cancer cell types. Concerning neuroprotection, astragalin ameliorates neuronal damage in Alzheimer’s disease models by activating PI3K/AKT-mTOR-mediated autophagy. Additionally, it reduces oxidative stress and ameliorates myocardial fibrosis associated with chronic heart failure. This review provides a theoretical foundation for the further investigation, development, and application of astragalin. |
