| 刊名 | Agricultural Biotechnology |
| 作者 | Emmanuel Godfrey Maneno1, Shiqi WEI1, Xi CHEN1,2, Mingxiao LI1, Shunlong MENG1,2*, Meshack Chubwa Maguru1 |
| 作者单位 | 1.Wuxi Fishery College, Nanjing Agricultural University, Wuxi 214081, China; 2.Scientific Observing and Experimental Station of Fishery Resource and Environment in the Lower Reaches of the Changjiang River, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China |
| DOI | DOI:10.19759/j.cnki.2164-4993.2026.01.006 |
| 年份 | 2026 |
| 刊期 | 1 |
| 页码 | 22-25 |
| 关键词 | Acute toxicity; Joint toxicity; Glyphosate isopropyl amine salt; Atrazine; Zebrafish (Danio rerio) |
| 摘要 | The widespread use of herbicides such as glyphosate isopropyl amine salt (GIS) and atrazine (ATZ) poses significant risks to aquatic ecosystems. This study investigated the single and joint acute toxicity of a 1:1 GIS-ATZ mixture on zebrafish (Danio rerio). Acute tests determined 96-h LC₅₀ values of 123.41 mg/L for GIS and 103.95 mg/L for ATZ. In the joint toxicity test, these values decreased to 60.96 and 50.88 mg/L, respectively. The Additive Index (AI) analysis revealed a consistent synergistic interaction between the herbicides at all exposure intervals. These findings underscore the enhanced ecological threat of herbicide mixtures and highlight the necessity of considering joint effects in environmental risk assessments. |