| 刊名 | Agricultural Biotechnology |
| 作者 | Rahma Mohamed Mahmoud1, Shiqi WEI1 , Xi CHEN1,2 , Mingxiao LI1, Shunlong MENG1,2* |
| 作者单位 | 1.Wuxi Fishery College, Nanjing Agricultural University, Wuxi 214081, China; 2. Scientific Observing and Experimental Station of Fishery Resource and Environment in the Lower Reaches of the Changjiang River, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China |
| DOI | DOI:10.19759/j.cnki.2164-4993.2025.06.005 |
| 年份 | 2025 |
| 刊期 | 6 |
| 页码 | 22-24 |
| 关键词 | Acute toxicity; Joint toxicity; Pendimethalin; Fenitrothion; Zebrafish (Danio rerio) |
| 摘要 | In this study, the single and combined acute toxicity effects of pendimethalin (herbicide) and fenitrothion (organophosphate insecticide) were investigated on juvenile zebrafish (Danio rerio) under semi-static conditions. Mortality was assessed at 24, 48, 72, and 96 h. The study revealed that pendimethalin exhibited higher toxicity than fenitrothion. The 96-h LC₅₀ values were 0.477 mg/L for pendimethalin and 2.634 mg/L for fenitrothion. Joint exposure produced enhanced toxicity, with 96-h LC₅₀ values of 0.204 mg/L (pendimethalin equivalent) and 1.139 mg/L (fenitrothion equivalent). Regression analysis showed a significant positive correlation (p < 0.05) between pesticide concentration and mortality, while toxicity indices confirmed synergistic interactions. These findings underscore the ecological risks posed by pesticide mixtures and highlight the importance of regulating pesticide use to safeguard aquatic organisms and maintain environmental sustainability. |
