| 刊名 | Agricultural Biotechnology |
| 作者 | Lei ZHANG1,2, Zhaoxia JIN3, Caixia ZHANG1, Jia SHI1, Manjia LI1, Wanying SU1, Yimin WANG1,2 Shuzhen WANG1,2, Feng HE1,2, Jinjun LUO4* |
| 作者单位 | 1．Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, Huanggang Normal University, Huanggang 438000, China；2. LiShizhen Culture and Industry Research Center of Traditional Chinese Medicine，Huanggang Normal University，Huanggang, 438000, China；3. Huanggang Central Hospital, Huanggang, 438000, China |
| DOI | DOI:10.19759/j.cnki.2164-4993.2025.02.004 |
| 年份 | 2025 |
| 刊期 | 2 |
| 页码 | 13-21,24 |
| 关键词 | Citespace; Epimedium brevicornu Maxim; Medicine food homology; Bibliometrics; VOSviewer |
| 摘要 | [Objectives] Epimedium brevicornu Maxim is a well-known plant having the concomitant function of both medicine and foodstuff with the bioactivity of anti-inflammatory and cardiovascular protection. It has important therapeutic effects and health benefits for various chronic diseases. This study aimed to analyze the studies on E. brevicornu Maxim from 2003 to 2022 with bibliometric analysis. [Methods] Publications related to E. brevicornu Maxim was retrieved in Web of Science Core Collection (WoSCC) from January 1, 2003 to November 19, 2022, and analyzed in Microsoft Excle, CiteSpace, and VOSviewer. [Results] In total, 1 317 documents were extracted from the WoSCC database. The growth rate of the publications showed a rapid increase from 2017. China provided the most documents, and Chinese Academy of Medical Sciences, Fudan University and Chinese Academy of Sciences contributed more papers. Wang Ying from Chinese Academy of Sciences was the most productive author, and the Journal of Ethnopharmacology was the most co-cited journal. The words "icariin", "activation", "oxidative stress", "apoptosis", "proliferation", "osteogenic differentiation" and "flavonoid" were frequently occurred in the abstract and title of articles. Cluster analysis of keywords demonstrated "hippocampal neuron", "efficient production", "liquid extraction", "bone regeneration" and "leukemia cell growth" were the hot topics from 2003 to 2022. The focus of the research has changed from the liquid extraction of flavonoids to the inflammatory response and metabolism, while cognitive deficit has emerged as a recent research hotspot. [Conclusions] The research on E. brevicornu Maxim has been expanding, and more studies are related to signaling pathways and metabolism diseases. |
