| 摘要 |
[Objectives] To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHN and its influence on inflammatory factors. [Methods] 96 patients with PHN were randomly divided into three groups: lotus needle cupping therapy group, TCM surrounding acupuncture group and gabapentin group. Venous blood and acupoint blood were collected at 0, 21 and 42 d of treatment, and the expression levels of 5-HT, SP and CGRP inflammatory mediators were detected before and after treatment. The changes of VAS scores before, during and after treatment and the clinical efficacy were observed. [Results] The total effective rate of the lotus needle cupping group was 87.50%, which was better than that of the TCM acupuncture group (81.25%) and the gabapentin group (62.50%); after treatment, the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment, and the decrease was more significant in the treatment group (P<0.05). [Conclusions] The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN, and its mechanism is to reduce the release of inflammatory mediators, reduce hyperalgesia, relieve pain and improve the quality of life of patients. |
