Quality Standard of Tibetan Medicine Nardostachys jatamansi Herba Based on "An Integrated Plant but Multi-purpose"
刊名 Medicinal Plant
作者 Hairong ZHONG, Yuebu HAILAI, Shaoshan ZHANG, Wenbing LI, Yuan LIU
作者单位 College of Pharmacy, Sichuan College of Traditional Chinese Medicine; Sichuan Provincial Qiang-Yi Medicinal Resources Protection and Utilization Technology and Engineering Laboratory; Key Laboratory of Protection and Utilization of Ethnic Medicinal Resources on Qinghai-Tibet Plateau, State Ethnic Affairs Commission; Southwest Minzu University
DOI 10.19601/j.cnki.issn2152-3924.2024.03.004
年份 2024
刊期 3
页码 16-22
关键词 Nardostachys jatamansi Herba, Chlorogenic acid, 3, 5-O-dicaffeoylquinic acid, Fingerprint, Quality standard, Resource utilization
摘要 [Objectives] To establish the quality standard of Nardostachys jatamansi Herba. [Methods] The characters and microscopical identification of N. jatamansi Herba were carried out. The contents of moisture, total ash, acid-insoluble ash and extract were determined according to the relevant methods of the Chinese Pharmacopoeia (2020 edition). Using chlorogenic acid and 3, 5-O-dicaffeoylquinic acid as quality control indexes, TLC and HPLC methods were established for qualitative and quantitative determination, and HPLC fingerprints were established. [Results] The characteristics of character identification, microscopic identification and thin layer identification were obvious. The moisture content ranged from 2.7% to 7.8%, with an average value of 5.4%. The total ash content ranged from 6.7% to 16.2%, with an average of 11.0%. The acid-insoluble ash content ranged from 0.7% to 8.5%, with an average of 3.6%. Extractives content ranged from 20.9% to 34.4%, with an average of 29.7%. Chlorogenic acid content was between 0.45% and 1.30%, with an average value of 0.77%. The content of 3, 5-O-dicaffeoylquinic acid ranged from 0.18% to 0.58%, with an average of 0.31%. The similarity of each batch was between 0.930 and 0.994, indicating that the quality of medicinal materials from different producing areas was stable. [Conclusions] The quality standard of N. jatamansi Herba was established, which could provide quality control basis for rational, comprehensive and efficient utilization of N. jatamansi DC. resources and clinical use.