Research Progress on Targets and Selective Inhibitors of Polo-like Kinase-1 (PLK-1)
刊名 Medicinal Plant
作者 Xin WANG, Qin ZENG, Guangying DU
作者单位 University Collaborative Innovation Center of Shandong Province, Key Laboratory of Molecular Pharmacology and Drug Evaluation of Ministry of Education, Yantai University
DOI 10.19601/j.cnki.issn2152-3924.2024.01.013
年份 2024
刊期 1
页码 51-56
关键词 Polo-like kinase-1, PLK-1 inhibitor, Cell cycle, Mitosis, Cancer
摘要 In this paper, the biological function of PLK-1, the correlation between PLK-1 and tumors, and the latest research progress on PLK-1 inhibitors under study are reviewed, in order to provide references for the research and development of PLK-1 inhibitors.