Anti-cancer, Anti-inflammatory, Antioxidant and Other Pharmacological Effects of Wedelactone and Their Molecular Mechanisms
刊名 Medicinal Plant
作者 Mingxinzhi WANG, Jingchao WANG, Xichun HUANG, Xinyu LIU, Quan QUAN, Chenghao JIN
作者单位 College of Life Science and Biotechnology, Heilongjiang Bayi Agricultural University
DOI 10.19601/j.cnki.issn2152-3924.2023.06.020
年份 2023
刊期 6
页码 84-87
关键词 Wedelactone, Anti-tumor, Anti-pulmonary fibrosis, Protection of blood vessels, Liver protection
摘要 Wedelolide is a coumarin-like active substance extracted from Ecliptae Herba. It not only has pharmacological effects of anti-pulmonary fibrosis, anti-arthritis, blood vessel protection and liver protection, but also effectively inhibits the proliferation of cancer cells and induces apoptosis of cancer cells, thereby delaying the further development of malignant tumors. In this paper, the pharmacological effects and mechanisms of wedelactone were reviewed to lay a foundation for further study and clinical application of wedelactone.