| 刊名 | Medicinal Plant |
| 作者 | Yifei LIN，Yamin ZUO，Tianjun LUO，Jie LU，Baohu ZHANG，Yan CHEN，Qing WU，Qin CHEN |
| 作者单位 | Key Laboratory of Mountain Environmental Information System and Ecological Environmental Protection； Hubei Key Laboratory of Wudang Local Traditional Chinese Medicine Research, School of Basic Medical Sciences, Hubei Medical University； Guizhou Remote Pharmaceutical Co.； Guizhou Cooperative Innovation Center of Biology and Information Technology in Karst Region； The Third Experimental Middle School of Guiyang City； College of Foreign Languages |
| DOI | 10.19601/j.cnki.issn2152-3924.2025.01.002 |
| 年份 | 2025 |
| 刊期 | 1 |
| 页码 | 11-15，69 |
| 关键词 | Longqing Capsule, Chemical component, Content determination, Quantitative analysis of multi-components by single marker (QAMS) |
| 摘要 | [Objectives] To establish a multi-indicator quality control method for the retention of Longqing Capsule based on the principle of prescription of Chinese medicine. [Methods] High performance liquid chromatography (HPLC) with ShimNex CS C18 as the column; column temperature: 35 ℃; wavelength: 270 nm; methanol-0.1% phosphoric acid solution as the mobile phase with gradient elution. [Results] The 12 components of the retention of Longqing Capsule showed good linearity within the investigated range (r≥0.999 5), with the average spiked recoveries of 97.83%-100.52% and the RSD of 0.9%-2.1%. [Conclusions] The method is exclusive, sensitive, reproducible, simple and easy to use, and can provide a reference for the construction of the quality standard and control system of Longqing Capsule based on the theory of traditional Chinese medicine. |
