| 刊名 | Animal Husbandry and Feed Science |
| 作者 | Li Kaixin, Chen Huan, Liu Fanglin, Liu Yong, Hou Hongwei, Hu Qingyuan |
| 作者单位 | China Tobacco Quality Supervision and Test Center; Key Laboratory of Tobacco Biological Effects; Beijing Institute of Life Science and Technology; Key Laboratory of Tobacco Biological Effects and Biosynthesis; University of Science and Technology of China; Hefei Institute of Physical Sciences |
| DOI | 10.19578/j.cnki.ahfs.2022.04-06.001 |
| 年份 | 2022 |
| 刊期 | 2 |
| 页码 | 1-8 |
| 关键词 | Nicotine dependence; Animal addiction models; Animal behavior; Rodents; Evaluation method |
| 摘要 | Nicotine is one of the most widely concerning components of cigarette smoke.Long-term intake of nicotine can lead to nicotine dependence that affects higher brain functions,which may involve anxiety,learning and memory impairments,and abnormal decision-making.To facilitate analyzing the molecular mechanisms of nicotine dependence,it is common to establish rodent nicotine dependence models to better understand the physiological changes.This paper summarizes and evaluates the application of animal behavior evaluation experiments in nicotine-dependent animal models,in order to provide a reliable reference for researchers to establish rodent nicotine-dependent models for evaluation. |
