The Origin of PRRSV and Advances in the Evolution and Pathogenicity of PRRSV 1 
刊名 Animal Husbandry and Feed Science
作者 Xu Xiaozhou, Zhang Zhendong, Xing Jun, Lian Xue, Shi Hongjing, Zhang Shoudong
作者单位 Jiangsu Vocational College of Agriculture and Forestry; College of Biotechnology, Jiangsu University of Science and Technology; Changjia(Shanghai)Agricultural Science and Technology Co.Ltd.
DOI 10.19578/j.cnki.ahfs.2022.01-03.005
年份 2022
刊期 1
页码 27-31
关键词 Porcine reproductive and respiratory syndrome virus(PRRSV); PRRSV genotype 1; Origin; Variation; Evolution; Pathogenicity
摘要 Porcine reproductive and respiratory syndrome virus(PRRSV) has been mutating and evolving constantly since its emergence in the1980s, which has brought inestimable economic losses to the global swine industry. The virus has two genotypes, of which genotype 1 PRRSV(PRRSV 1) first broke out in Germany and mainly prevailed in Europe, which can be clustered into four subtypes based on the ORF5 sequence. Al-though few cases of PRRSV 1 have been reported in China, the prevention and control of PRRSV should not be ignored. The origin of PRRSV, ge-netic evolution and pathogenicity of PRRSV 1 were retrospectively analyzed, in order to provide valuable evidences for molecular epidemiology and immune prevention and control of PRRSV 1.