| 刊名 | Agricultural Biotechnology |
| 作者 | Xiaojing WEI1, Binjing ZHAO1, Xinyi JIANG1, Rui WANG1,2 |
| 作者单位 | 1. School of Pharmacy, Guilin Medical University, Guilin 541199, China; 2. Guangxi Key Laboratory of Drug Discovery and Optimization, School of Pharmacy, Guilin Medical University, Guilin 541199, China |
| DOI | DOI:10.19759/j.cnki.2164-4993.2024.04.012 |
| 年份 | 2024 |
| 刊期 | 4 |
| 页码 | 50-53,62 |
| 关键词 | Necroptosis; Digestive diseases; RIP1; RIP3; MLKL |
| 摘要 | Digestive system diseases refer to organic and functional disorders of the digestive system, which are prone to recurrence and frequently accompanied by multiple complications. Necroptosis is a regulated mode of cell death mediated by death receptors, dependent on receptor protein activation, and could be specifically inhibited by necrostatin-1. Necroptosis is involved in pathological and physiological processes of various diseases, and plays an important role in the growth and development of organisms and the homeostasis of organ tissues. This paper reviewed the research advancement of necroptosis in digestive system disorders, and discussed the relationship between necroptosis and digestive system diseases, aiming to provide theoretical basis for the cure of these diseases. |
