Bacteriostatic Effect of Self-designed Chinese Herbal Formula and Its Application in Preparing Traditional Chinese Medicine Acne-removing Soap
刊名 Agricultural Biotechnology
作者 Caien CAI1, Yingxi QIN1, Tingli SU1, Hailin LU1,2*, Bin LI*
作者单位 1. Guangxi University of Chinese Medicine, Nanning 530200, China; 2. National Demonstration Center for Experimental Education of Chinese Materia Medica, Guangxi University of Chinese Medicine, Nanning 530200, China
DOI DOI:10.19759/j.cnki.2164-4993.2025.03.017
年份 2025
刊期 3
页码 71-74,83
关键词 Chinese medicine formula; Acne; Antibacterial effect; Staphylococcus aureus; Staphylococcus albus; Propionibacterium acnes
摘要 [Objectives] This study was conducted to investigate the antibacterial effect of a self-designed acne-relieving Chinese herbal formula and prepare a kind of acne-removing soap according to the antibacterial effect. [Methods] Chinese herbs Lonicera japonica, Taraxacum mongolicum, Scutellaria baicalensis, Angelica dahurica, Centella asiatica and Aloe vera, were decocted with water, and the antibacterial effects on Staphylococcus aureus, Staphylococcus albus, Candida albicans and Propionibacterium acnei were tested by inhibition zone experiments. The soap base was prepared by saponification of coconut oil, palm oil, hazelnut oil and sodium hydroxide, and then the herbal liquid was added into the soap. [Results] The liquid had bacteriostatic effect on S. aureus, S. albus and P. acnes, but no inhibitory effect on C. albicans. The best bacteriostatic effect on S. aureus and S. albus was achieved at 330 mg/ml, and the best bacteriostatic effect on P. acnes was at 160 mg/ml. [Conclusions] The Chinese herbal formula has antibacterial effect. The handmade soap made from the Chinese herbal formula has the characteristics of smooth surface, moderate hardness, fine texture, rich foam and fresh smell.