| 刊名 | Agricultural Biotechnology |
| 作者 | Jinmei XIANG1,2, Wenqin CHEN2, Qingguang LAI3, Fulai YU3, Ruju LI3, Miaomiao ZHANG2, Kai YANG2, Nini GUO2, Wenxi WANG2, Xianrong SONG2, Chunyun WAN1* |
| 作者单位 | 1. College of Animal Science, Yangtze University, Jingzhou 434023, China; 2. Department of Animal Science, Hubei Vocational College Of Bio-Technology, Wuhan 430070, China; 3. Zhejiang MEBOLO Biotechnology Co., Ltd, Jinhua 321000, China |
| DOI | DOI:10.19759/j.cnki.2164-4993.2025.03.011 |
| 年份 | 2025 |
| 刊期 | 3 |
| 页码 | 45-46,50 |
| 关键词 | Haemophilus parasuis; Pig farm; Vaccine |
| 摘要 | [Objectives] This study was conducted to evaluate the practical efficacy of Haemophilus parasuis (Hps) vaccines and determine whether the continuous use of vaccines leads to changes in Hps serotypes. [Methods] A swine production group that had used a bivalent vaccine of Hps serotypes 4 and 5 for two consecutive years were investigated and retrospectively analyzed. Data on Hps detection rate, nursery production and disease indexes, as well as serotype shifts after continuous vaccination, were collected to assess vaccine effectiveness. [Results] Continuous vaccination reduced the total nursery culling and mortality rate by 1.75%. Hps infection persisted in the farms, and the pathogen could still be isolated. However, serotyping revealed a significant shift in the dominant prevalent serotypes, indicating that the vaccine was indeed effective. [Conclusions] The matched Hps vaccine demonstrated effective results. However, whether replacing serotypes or adding more prevalent serotypes could further improve the control of Hps disease requires further investigation. |
